What is gout is increasing worldwide!

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Gout, which is one of the diseases that is increasing worldwide, is a joint disease with symptoms such as pain, swelling and fever in the body. What is gout with an interesting name? What are the gout treatment methods? Here are all the details you need to know about gout, Internal Medicine Specialist Assist. Assoc. Dr. Sedat Özdemir informed his readers of ellema.com. Is gout contagious? Is there a cure for gout? Here are the details you need to know about gout.

What Are Gout Symptoms?

Gout is an inflammatory arthritis that occurs after the accumulation and crystallization of Monosodium Urate Monohydrate (MSU) in the joints. In other words, it is the formation of a rheumatic disease picture with pain, swelling, redness, fever (increase in temperature in the joints) caused by the accumulation of MSU crystals in the joints.The risk of developing the disease is higher in men. Gout is a common joint disease in men and elderly women. Exposure to the disease is increasing worldwide. The cause of the disease is the excessive increase of urate ions in the blood and body fluids. In other words, it occurs when the level of uric acid, which is the end product of protein (purine) metabolism, increases excessively.

Therefore, it is also known as the disease of the rich. Under normal conditions, a uric acid level in the blood above 6.8 mg/dl is considered to be excessively high. Although high uric acid levels are necessary for the development of gout, gout does not occur in all patients with high uric acid levels, and it occurs in only a few (15%-25%). The higher the uric acid level in the blood, the higher the risk of gout. Gout is a progressive disease involving one or more joints with attacks in the leg joints. It can become chronic over the years, causing loss of function of the joint.Uric acid accumulates in soft tissue and kidneys, causing cellulite formation, kidney stone formation and kidney disease.

In the increase in the incidence of the disease;

  • prolongation of human life,
  • Hypertension,
  • metabolic syndrome and obesity,
  • Some drugs (frequent use of low-dose acetylsalicylic acid and thiazide diuretics)
  • Excessive use of high fructose corn syrup as a sweetener,
  • Dietary trend changes,
  • Patients with end-stage renal disease,
  • Organ transplant patients are among the effective causes.

Men suffer from gout 3-6 times more often than women.
Two-thirds of the uric acid formed in the body is excreted from the kidneys and one-third from the intestines. in gout patients
Uric acid excretion from the kidneys decreased by 90%. 10% of gout patients are caused by excess uric acid production or a combination of both overproduction and decreased excretion from the kidneys.

Causes of decreased excretion from the kidneys;

  • Genetic factors (Primary hyperuricemia),
  • kidney diseases,
  • Endofon organic acid accumulation
  • There may be some drugs.

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Some drugs increase the excretion of uric acid from the kidneys. The reasons for the increase in the formation of uric acid are;

  • Diseases caused by some enzyme deficiency,
  • some blood diseases,
  • Situations where blood destruction increases,
  • Obesity,
  • Psoriasis,
  • some drugs,
  • Alcohol,
  • Red meat, offal, shellfish,
  • Fructose.

The course of gout has 3 stages;

1) Asymptomatic Hyper Uricemia: It is the period when uric acid is high in the blood but the disease does not occur.
2) Acute Intermittent Gout: The period in which the first gout attack occurs and the attacks recur for 5-8 days.
3) Chronic Advanced Gout

The first period, in which there are no symptoms, no disease, but high uric acid level, can last for years in silence. Gout does not occur in every person with high uric acid level. The first attack occurs years after uric acid elevation in men at the age of 40-50 years, and in women after menopause. Classic gout is characterized by rapidly developing heat, swelling, redness and extreme pain in one or sometimes both joints. The most commonly involved joint is the 1st finger joint of the foot. (called podagra). This is followed by the ankle and knee joints. After years, wrist, elbow and hand finger joints may also be affected.

Sometimes fever, chills and weakness can be observed with joint findings. This gout attack can be triggered by traumas, surgical procedures, fasting, excessive consumption of high protein drinks, and drugs that affect serum and uric acid levels. Small swellings formed by the accumulation of uric acid under the skin are called tophi. These are indications that gout is progressing. Tophus are most common on the fingers, wrists, ears, knees, and arms.

How Does Gout Treatment Proceed?

  • Diet and weight loss, increasing fluid intake,
  • Avoiding high protein (purine) foods,
  • Reducing alcohol intake,
  • Lowering the uric acid level and
  • Medications are recommended.

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